The FDA has approved Alnylam Pharmaceuticals' Onpattro, or patisiran, for the treatment of polyneuropathy in patients with hereditary ATTR amyloidosis, making it the first gene-silencing drug to win US approval. Onpattro will carry an annual list price of $450,000 for the average patient, and several insurers, including Harvard Pilgrim Health Care, agreed to cover the drug through value-based deals with Alnylam.
Leaders will have more influence when they develop themselves professionally, help others improve and maintain the organization's strategic alignment, says John Baldoni in this SmartBrief video and blog post. "Savvy managers always ensure alignment by making certain people know their roles and how those roles affect overall results," he says
A study in Pediatrics showed that autism spectrum disorder incidence was 3.78 per 1,000 person-years among children whose mothers received the Tdap vaccine during pregnancy, compared with 4.05 per 1,000 person-years among those whose mothers weren't vaccinated during pregnancy. Prenatal Tdap vaccination was more likely among Asian-Americans or Pacific Islanders, those who were nulliparous, those with at least a bachelor's degree and those who gave birth at 37 or more weeks' gestation.
Tired of waiting for the Trump administration to solve their health care challenges, state governments are taking matters into their own hands to ensure residents have access to health care coverage. Some of the actions taken by states include expanding Medicaid eligibility, establishing mandates that individuals enroll in health coverage, introducing bills to address prescription drug prices and approving measures to restrict access to short-term health plans.
Researchers who analyzed data from HIMSS Analytics' eight-stage EMR Adoption Model collected between 2006 and 2014 found that although the number of hospitals at stages 5 and 6 should peak by 2019 and 2026, respectively, the number of hospitals on Stage 7 will not peak by 2035. The findings in the Journal of Medical Internet Research indicated that "US hospitals are decades away from fully implementing sophisticated decision support applications and interoperability functionalities in EHRs," the authors wrote.
Researchers followed 94,000 individuals, ages 35 to 70, for an average of eight years and found an association between high sodium intake and increased risk of cardiovascular disease and stroke, but only in communities where the average intake was greater than 5 grams per day, or about 2.5 teaspoons of table salt. The findings in The Lancet revealed that sodium consumption in communities with less than 5 grams of sodium consumed daily was inversely associated with heart attack and total mortality.
Researchers looked at data from 15 countries and found lower levels of absenteeism and higher levels of presenteeism when managers are supportive of employees with depression. The study in BMJ Open also showed employees who live in a country with more managers who avoid discussing depression tended to have more work absences.
The expectation that employees will check email when they are not at work can cause anxiety and stress, researchers reported at the Academy of Management's annual meeting and in Academy of Management Proceedings. The study of 100 employees found some said monitoring their work email also led to higher levels of anxiety and conflict with their spouse.
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